Oncolytic virus
Traits, Modifiers & Hosts That Change Cancer
Real oncolytic viruses are engineered to infect and burst cancer cells. In StrainBorn, a trait, run modifiers, host conditions, host genes and a city policy can make tumors weaker, richer, faster or more common.
A Cancer trait from mutation orbs: deal more damage to tumors and all their cells, assassins included.
Oncolytic viruses infect and burst cancer cells; some are approved cancer treatments.
Oncolytic Payload in the Codex
A run modifier crafted between runs: tumors take double damage and pay out double, but every organ grows a tumor.
Consumables crafted between runs that change the next run.
Fun fact: A loaded modifier stays loaded until you run out of it.
Run Modifiers in the CodexA run modifier crafted between runs: tumors pay out triple, but grow twice as fast and start a stage bigger.
Consumables crafted between runs that change the next run.
Fun fact: A loaded modifier stays loaded until you run out of it.
Run Modifiers in the CodexLoad Oncolytic Strain and Carcinogen Exposure together and destroying a tumor heals you fully.
Consumables crafted between runs that change the next run.
Fun fact: A loaded modifier stays loaded until you run out of it.
Run Modifiers in the CodexOncolytic Strain, Carcinogen Exposure and Nutrient Cache together: tumors pay 50% more and destroying one heals you fully.
Consumables crafted between runs that change the next run.
Fun fact: A loaded modifier stays loaded until you run out of it.
Run Modifiers in the Codex
The host is riddled with cancer: every organ grows a tumor that starts a stage bigger, grows faster and spreads twice more. Tumors pay out triple.
Metastasis is when cancer spreads from where it started to other organs through the blood or lymph.
A condition people can have.
Metastatic Cancer in the Codex
The drugs wipe out immune cells and shrink tumors, but poison you too.
Chemotherapy kills fast-dividing cells: cancer, but also immune cells, which is why patients catch infections easily.
A condition people can have.
Chemotherapy in the Codex
A helpful host gene: p53, the guardian of the genome, slows tumor growth.
The person or animal you infect at the start of a run.
Fun fact: Rarer hosts have bigger effects and pay more nucleotides.
Hosts & Host Traits in the CodexA harmful host gene found only in people: cells can't repair DNA, so cancers grow faster and spread further.
The person or animal you infect at the start of a run.
Fun fact: Rarer hosts have bigger effects and pay more nucleotides.
Hosts & Host Traits in the Codex
Take Mexico City in Pandemic Game Mode and this policy puts a tumor in every organ, growing faster but paying double.
In April 2009 the new H1N1 'swine flu' was identified in Mexico. Mexico City closed schools, restaurants and stadiums for days to slow what became the first pandemic of the century.
Fun fact: Mexico · population 21.8 million · North America
Mexico City in the Codex
While CRISPR is active, tumor cells you touch are cut apart, but cores and the leukemic stem cell resist.
A bacterial immune system that remembers viruses and cuts their DNA with the Cas9 enzyme; scientists adapted it into a precise gene-editing tool.
Fun fact: Its discoverers, Jennifer Doudna and Emmanuelle Charpentier, won the 2020 Nobel Prize in Chemistry.
CRISPR-Cas9 in the Codex
