
Organ 3 of 8
Bloodstream
A rushing crimson vessel. The blood flow shoves you along with every heartbeat while red blood cells stream past. Ride the current to the Plasma Cell.

Who you meet here
BossPlasma CellThe antibody factory. It drifts and strafes behind a turning Immunoglobulin wall, so you have to circle around it…
Key guardianFibrin WeaverA living clot guarding the Plasminogen Activator. Keep clear of where its fibrin lands.
GenePlasminogen ActivatorDissolves fibrin clots. Platelet clots no longer slow you.
CancerLeukemiaA crowd of white blast cells that keep dividing. One gold leukemic stem cell hides among them: kill it and the whole…
AssassinCirculating BlastA blast cell bristling with needle-like Auer rods. The fastest assassin of all.Organ facts
- Objective
- "Ride the current to the Plasma Cell"
- Boss
- Plasma Cell, "The immune system's antibody factory"
- Key guardian
- Fibrin Weaver, holding the Plasminogen Activator. One door is sealed by a fibrin clot
- Cancer
- Leukemia (cancer cells keep dividing, so find and kill the glowing stem cell). Its assassin is the Circulating Blast
- Hazards
- a pulsing blood flow and solid red blood cells. There are no nerve endings here because blood has no sensory endings
- Local cells
- Platelets in clumps, Neutrophils, Natural Killer Cells, Complement, Macrophages, Monocytes, Plasmablasts and Basophils. Deeper rooms add Dendritic Cells, antiviral capsules, vaccine vials and Memory B Cells
- Look
- a deep red floor with streams of red blood cells and streaks of flow, inside a vessel wall lined with flat endothelial cells and rings of smooth muscle
- Music
- B-flat harmonic minor at 116 BPM with a square-wave lead
- Size
- 17–21 rooms
- Threat
- enemy damage ×1.2, enemy health ×1.85, rewards ×2.2
Also in the Bloodstream
Tissue Hazards & TerrainOrgans & Bosses
Red Blood CellsSolid discs drifting with the pulsing blood flow. They shove you around and soak up shots from both sides.Bloodstream
Clots & Scar TissueSticky patches of clot left by dying platelets, fibrin attacks, goblet mucus and stellate scarring. They bog you right down.Bloodstream & deeper
Blood FlowThe current pushes you in pulses that are strongest on each heartbeat, about 69 beats a minute.BloodstreamTumor PartsCancer
Leukemic blastA white cell almost filled by its nucleus. Blasts chase you and keep dividing.Bloodstream
Leukemic stem cellThe gold-tinted, glowing cell that drives the leukemia. Kill it and every blast dies with it.BloodstreamTumor AttacksCancer
Organ MilestonesViruses
The Organ MapIn a Run
Boss SetsGear & Store
Audio & PresentationGame Modes
Found in every organ
From the Codex
The network of vessels carrying about 5 litres of blood around the body every minute, filled with red cells, platelets and immune cells.
Fun fact: Laid end to end, your blood vessels would stretch around 100,000 km, more than twice around the Earth.
Bloodstream in the Codex











