Modifier Combos

Consumables crafted between runs that change the next run.

Fun fact: A loaded modifier stays loaded until you run out of it.

A change in a genome's sequence. Most are harmless or harmful, and a few help the organism survive.

Fun fact: Flu's RNA polymerase doesn't proofread, so it makes errors constantly.

Consumables crafted between runs that change the next run.

Fun fact: A loaded modifier stays loaded until you run out of it.

The building block of DNA and RNA: a sugar, a phosphate and a base (A, T, C, G in DNA; A, U, C, G in RNA).

Fun fact: Influenza stores its genes as RNA, so it uses U in place of T.

Some viruses grow by consuming host resources, at the cost of host recovery.

A quick burst of movement.

Fun fact: Dash through attacks rather than away from them. Watch out for thymocytes, which copy your dash.

Consumables crafted between runs that change the next run.

Fun fact: A loaded modifier stays loaded until you run out of it.

A bacterial immune system that remembers viruses and cuts their DNA with the Cas9 enzyme; scientists adapted it into a precise gene-editing tool.

Fun fact: Its discoverers, Jennifer Doudna and Emmanuelle Charpentier, won the 2020 Nobel Prize in Chemistry.

A mass of the body's own cells dividing out of control. Some viruses, like Epstein-Barr (linked to nasopharyngeal carcinoma) and HPV, can help trigger cancers.

Fun fact: Oncolytic viruses are engineered to infect and burst cancer cells; one (T-VEC, a modified herpes virus) is approved to treat melanoma.

Short bursts of elemental power, and the rare CRISPR.

Fun fact: Different power-ups run at the same time, and they follow you into the next room.

A change in a genome's sequence. Most are harmless or harmful, and a few help the organism survive.

Fun fact: Flu's RNA polymerase doesn't proofread, so it makes errors constantly.

The slower, targeted immune response that learns the specific features of a pathogen and remembers them.

Fun fact: Vaccines work by training this system without the real disease.

Other viruses competing for the same host.

Fun fact: Rivals don't lock the doors, so running is always an option.

The time between catching a virus and feeling sick. The virus is multiplying, but the body hasn't noticed yet, so there are no symptoms.

Fun fact: Flu incubates for about 1–4 days, measles about 10–12, and rabies can take months; HIV's silent clinical latency can last 10 years.

A sticky gel made of water and mucins that traps dust and microbes before they reach deeper airways.

Fun fact: Your airways make roughly a litre of mucus a day.

A "killer" T cell that hunts down infected cells and destroys them by punching holes with perforin and injecting granzymes.

Fun fact: Each killer T cell is trained to recognise one specific antigen, then multiplies into an army once it finds a match.

The host feeling sick and taking medicine when Detection is 75 or more.

Fun fact: Walking out of the room escapes a dose; surviving it pays out.

An outer lipid membrane some viruses steal from the host cell as they bud out of it, studded with the virus's own glycoproteins.

Fun fact: Enveloped viruses like flu and HIV are fragile outside the body: soap dissolves their envelope.

Every room rolls a tier, from common to prismatic, with boons and drawbacks.

Fun fact: Check a room's border colour on the minimap before you walk in.

Consumables crafted between runs that change the next run.

Fun fact: A loaded modifier stays loaded until you run out of it.

The building block of DNA and RNA: a sugar, a phosphate and a base (A, T, C, G in DNA; A, U, C, G in RNA).

Fun fact: Influenza stores its genes as RNA, so it uses U in place of T.

Some viruses grow by consuming host resources, at the cost of host recovery.

Your three special buttons on the right.

Fun fact: Save the ultimate for bosses and big waves.

How aware the host's immune system is of you, from 0 to 100. It's the bar next to the eye at the top of the screen, and the more it fills, the harder the immune system fights back.

Fun fact: Stay out of fights for a few seconds and the bar drains on its own. Refuge rooms drop it fast.

A change in a genome's sequence. Most are harmless or harmful, and a few help the organism survive.

Fun fact: Flu's RNA polymerase doesn't proofread, so it makes errors constantly.

A bacterial immune system that remembers viruses and cuts their DNA with the Cas9 enzyme; scientists adapted it into a precise gene-editing tool.

Fun fact: Its discoverers, Jennifer Doudna and Emmanuelle Charpentier, won the 2020 Nobel Prize in Chemistry.

Short bursts of elemental power, and the rare CRISPR.

Fun fact: Different power-ups run at the same time, and they follow you into the next room.

A mass of the body's own cells dividing out of control. Some viruses, like Epstein-Barr (linked to nasopharyngeal carcinoma) and HPV, can help trigger cancers.

Fun fact: Oncolytic viruses are engineered to infect and burst cancer cells; one (T-VEC, a modified herpes virus) is approved to treat melanoma.

The slower, targeted immune response that learns the specific features of a pathogen and remembers them.

Fun fact: Vaccines work by training this system without the real disease.

Other viruses competing for the same host.

Fun fact: Rivals don't lock the doors, so running is always an option.

The time between catching a virus and feeling sick. The virus is multiplying, but the body hasn't noticed yet, so there are no symptoms.

Fun fact: Flu incubates for about 1–4 days, measles about 10–12, and rabies can take months; HIV's silent clinical latency can last 10 years.

Extra health bars that soak damage before a cell's health.

Fun fact: Match your damage to the defence: electric for shields, explosive for armor.

Every room rolls a tier, from common to prismatic, with boons and drawbacks.

Fun fact: Check a room's border colour on the minimap before you walk in.

Many viruses spread before symptoms appear, staying under the immune system's radar.