
Organ 7 of 8
Bone Marrow
The blood-cell factory inside the bone: pale trabecular struts and fat cells, where megakaryocytes shed platelets and myeloblasts burst into neutrophils.

Who you meet here
BossHematopoietic Stem CellThe mother of every blood cell. It keeps making new ones (neutrophils, myeloblasts, platelets, even megakaryocytes and…
Key guardianGiant OsteoclastA huge bone-dissolving cell (Ancient) guarding the Mucolytic Enzyme. It burrows after you and erupts where it surfaces.
GeneMucolytic EnzymeDissolves mucus plugs. Mucus no longer slows you.
CancerMultiple MyelomaA malignant plasma cell drifting in slow circles, firing spirals of Y-shaped antibodies that lock on to you and…
AssassinLytic StalkerA jagged bone shard. Where its pounce lands it punches a small bone lesion that hurts to stand in.Organ facts
- Objective
- "Take over the Hematopoietic Stem Cell"
- Boss
- Hematopoietic Stem Cell, "Mother of every blood cell"
- Key guardian
- Giant Osteoclast (Ancient), holding the Mucolytic Enzyme
- Cancer
- Multiple Myeloma (dodge its antibody spirals when they lock on, and keep off the bone lesions). Its assassin is the Lytic Stalker
- Hazards
- stem cell niches you can burst for health
- Local cells
- Myeloblasts, Megakaryocytes, Platelets, Neutrophils, Monocytes, Plasmablasts, Eosinophils and Lymphoid Progenitors. Deeper rooms add NKT Cells, Helper T Cells and vaccine vials
- Look
- a bone-brown floor crossed by cream bone struts and pale fat cells, inside hard, pale bone walls honeycombed with marrow pores
- Music
- E-flat harmonic minor at 120 BPM, the fastest theme
- Size
- 21–25 rooms
- Threat
- enemy damage ×9.5, enemy health ×28, rewards ×4.7
Also in the Bone Marrow
Tissue Hazards & TerrainOrgans & Bosses
Stem Cell NichesA pod of young blood cells. Burst it to heal, but fresh neutrophils pour out.Bone Marrow
Clots & Scar TissueSticky patches of clot left by dying platelets, fibrin attacks, goblet mucus and stellate scarring. They bog you right down.Bloodstream & deeperTumor PartsCancer
Myeloma coreA malignant plasma cell with an off-centre nucleus, stuffed with stored antibody and studded with Y-shaped M-proteins.Bone Marrow
Myeloma cloneA small oval plasma cell that keeps its distance, circling you and firing single antibodies.Bone MarrowTumor AttacksCancer
M-protein spiralA spiral of Y-shaped antibodies that flare, then all turn at once toward where you are standing.Bone Marrow
Bone lesionsMarked circles at and around you collapse into punched-out holes in the bone.Bone Marrow
Antibody shotMyeloma clones fire single Y-shaped antibodies at you while circling at range.Bone MarrowOrgan MilestonesViruses
The Organ MapIn a Run
Boss SetsGear & Store
Audio & PresentationGame Modes
Found in every organ
From the Codex
Soft tissue inside bones where every blood cell is made: hundreds of billions a day, from a small pool of stem cells.
Fun fact: Your marrow makes about 2 million new red blood cells every second.
Bone Marrow in the Codex











