A real-science encyclopedia of everything in the game: 390 entries in 15 categories. 40 Game Mechanics entries explain how the game works; the other 350 are discovered as you play, each with its real-world biology, a fun fact and what it does in the game.
Categories on the left, that category's entries in the middle, and the entry to read on the right.
“N / 350 discovered” in the header; each category shows found/total and turns mint when complete
Undiscovered entries read “???” with a silhouette and a hint on how to find them
Entries show REAL WORLD, FUN FACT and IN GAME (Game Mechanics: WHAT IT IS, TIP, HOW IT WORKS)
‹ › page through what you've found; L1/R1 or Q/E flip categories
Opens at the entry you came for when reached from the drops guide
Opens after your first finished run
From the Codex
How aware the host's immune system is of you, from 0 to 100. It's the bar next to the eye at the top of the screen, and the more it fills, the harder the immune system fights back.
Fun fact: Stay out of fights for a few seconds and the bar drains on its own. Refuge rooms drop it fast.
How the game's systems work, from Detection and Hunter Squads to Endless Game Mode and Pandemic responses.
Always readable, never “discovered”
Gated mechanics appear once they've been introduced in a run
Examples: Detection, Killer T Cells, Room Tiers, Strains & Lineage, Starting Deeper, Run Modifiers, Pandemic Game Mode Responses
From the Codex
How aware the host's immune system is of you, from 0 to 100. It's the bar next to the eye at the top of the screen, and the more it fills, the harder the immune system fights back.
Fun fact: Stay out of fights for a few seconds and the bar drains on its own. Refuge rooms drop it fast.
The six gear slots, the real viral parts behind them, and the Viral Genome.
Capsid, Viral Envelope, Matrix Protein, Tail Fibers, Spike Protein
Unlocks when you find gear for that slot
From the Codex
The protein shell that encloses a virus's genome, built from repeating subunits called capsomeres. Most are icosahedral (20 triangular faces) or helical.
Fun fact: Capsids self-assemble: the proteins snap together on their own, like a puzzle that builds itself.
Every animal you can infect, each with its own signature trait.
Unlocks when you infect one
Some only live around Pandemic Game Mode cities
Examples: Fruit Bat, Pig, Dromedary Camel, Kangaroo, Penguin
From the Codex
Bats are the natural reservoir of some of the deadliest viruses known: Marburg, Nipah, Hendra, rabies, and the ancestor of the 2003 SARS virus. Ebola is strongly suspected to come from bats too. Their immune systems tolerate viruses without the damaging inflammation that sickens other mammals.
Fun fact: Bats are the only mammals that truly fly; the fever-like heat of flight may help them keep viruses in check.
Every Pandemic city, with a real outbreak or event from its history.
Unlocks when you start a run there in Pandemic Game Mode
Shows country, population and continent, its standing policy and what it becomes once taken
From the Codex
During the 1918–1920 flu pandemic Japan's government put up posters urging people to wear masks in crowds, the start of Japan's long mask-wearing habit.