Brain

Who you meet here

BossMicrogliaThe brain's last line of defence: a branching violet cell that lashes in every direction, summons glia and strikes…Key guardianBetz CellA giant motor neuron (Ancient) guarding the Fusion Peptide. Watch the lines: it leaps along them in a chain, then goes…GeneFusion PeptideSlips through tight junctions. Your dash damages cells you pass through.CancerGlioblastomaA brain tumor rooted among glial nodes. Tendrils creep across the floor at you, and the core hops between nodes. Cut…AssassinGlial InfiltratorA narrow cell trailing long, wavy processes. After its pounce it re-aims and pounces a second time, straight away.

Organ facts

Objective

"Cross the barrier and defeat the Microglia"

Boss

Microglia, "The brain's last line of defence". Beating it wins the run

Key guardian

Betz Cell (Ancient), holding the Fusion Peptide

Cancer

Glioblastoma (tendrils creep toward you and the core hops between nodes, so cut the nodes down). Its assassin is the Glial Infiltrator

Hazards

synapses that arc between neuron pairs, and the blood-brain barrier, announced as you arrive

Local cells

Astrocytes, Resident Memory T Cells, NK Cells, Monocytes, Free Antibodies, Thymocytes and Memory B Cells. Deeper rooms add NKT Cells, Follicular Dendritic Cells, antiviral capsules and vaccine vials

Look

a deep indigo floor with a web of neurons and sparks running along it, inside walls of folded grey matter with glinting synapses

Music

C Lydian at 88 BPM, the slowest and brightest theme

Size

22–26 rooms

Threat

enemy damage ×12.5, enemy health ×34, rewards ×5.5

Also in the Brain

Tissue Hazards & TerrainOrgans & Bosses

SynapsesPairs of neurons that fire an electric arc between them every few seconds after a flickering warning.BrainClots & Scar TissueSticky patches of clot left by dying platelets, fibrin attacks, goblet mucus and stellate scarring. They bog you right down.Bloodstream & deeperBlood-Brain BarrierThe brain's shield. Every hostile cell in the Brain takes 38% less damage from you.Brain

Tumor PartsCancer

Glioblastoma coreA purple mass with a dark, dead heart and a rim of crowded cells, reaching out with infiltrating processes.BrainGlial nodeA slowly spinning, star-shaped tumor cell with long branching arms. Tendrils grow from it, and the core hops between nodes.Brain

Tumor AttacksCancer

Creeping tendrilsTendrils creep slowly across the floor at you, hold for 2 seconds, then pull back. Touching one hurts.BrainNode hopThe core marks a spot by a node with a purple ring, shrinks, slips under the floor and travels there.BrainPulse ringsSurfacing, the glioblastoma fires two rings of shots, each with a gap to slip through on opposite sides.Brain

Organ MilestonesViruses

Retrovirus: BrainCaptured cells double their damage and toughness, and Latency and Integration Surge hit 120% harder.Organ 8Halovirus: BrainInfection, spike volleys, outbreaks and the ultimate hit 90% harder.Organ 8

The Organ MapIn a Run

BrainCross the barrier and defeat the Microglia to win the run.Organ 8

Boss SetsGear & Store

Neurotropic CrownThe Microglia's set, built for critical hits and burst damage.Organ 8 · Brain

Audio & PresentationGame Modes

Brain themeThe brightest theme, for the final organ.Organ 8

Found in every organ

Abyss PitsBottomless gaps in the tissue. Falling in is a heavy blow, not instant death.Any organDrop ShaftsA rare glowing shaft in one of an organ's deeper fight rooms. Walk in and the current sweeps you into a freshly shuffled layout of the…Rare

From the Codex