Wiki In a Run Power-ups Power-ups drop from the first five cells you kill in a fight (never the last cell standing), so there's always a fight left to use them on. An elemental power-up turns up in about 1 fight in 8, with a random element; CRISPR, the rarest, in about 1 fight in 125. Several different ones can run at once, picking up one you already have adds its full duration, and all of them wear off when you enter a new organ. Numbers below are at base strength; Elemental Potency makes them stronger.
On this page 11 CRISPR Spike Shield Chain Lightning Fire Cross Tidal Pulse Gale Force Stone Skin Frost Aura Mist Veil Radiance Umbra Like a star: for 10 seconds you're invincible and faster, and every cell you touch is cut apart.
10 s, +45% move speed, untouchable Ordinary cells you touch are destroyed outright Bosses, mini-bosses and tumor cores take 4× your damage every 0.5 s instead The screen edges glow rainbow and a CRISPR countdown shows at the top A short grace period after it ends lets you get clear From the Codex A bacterial immune system that remembers viruses and cuts their DNA with the Cas9 enzyme; scientists adapted it into a precise gene-editing tool.
Fun fact: Its discoverers, Jennifer Doudna and Emmanuelle Charpentier, won the 2020 Nobel Prize in Chemistry.
CRISPR-Cas9 in the Codex Run over cells to shred them; nothing can hurt you.
Invincible for 6 s, +15% move speed Each touch deals 1.3× your damage and shoves the cell aside A short grace period after it ends From the Codex Coronaviruses are named for the crown of spike proteins covering them; the spikes grab and pierce their way into cells.
Spike Shield in the Codex Lightning arcs out of you and chains between cells.
About every half second, a bolt chains through up to 4 cells 0.9× your damage per cell, as electric damage From the Codex Nerves and muscle cells fire with electrical signals; some viruses, like rabies, travel along nerves to reach the brain.
Chain Lightning in the Codex Four flamethrower jets spin around you, setting cells burning.
Jets reach about 165 points Hits every 0.15 s for 0.3× your damage, plus burning for 3 s From the Codex Waves pulse out of you, pushing cells back and washing away shots.
A wave every 0.8 s for 0.5× your damage, with knockback Clears enemy shots inside the wave From the Codex You move much faster and blow enemy shots back at them.
About +35% move speed Nearby enemy shots turn around and hit cells for 0.8× your damage Pushes nearby cells away From the Codex Take far less damage while boulders orbit you, crushing cells and blocking shots.
Take 55% less damage 3 orbiting boulders hit for 1.4× your damage and stop enemy shots From the Codex Some infections leave calcified scars behind, hard lumps of minerals the body builds around damaged tissue.
Stone Skin in the Codex Every cell near you is slowed, and may freeze solid for a moment.
Slows cells in the aura by 35% (bosses half as much) Chills for 0.12× your damage every 0.25 s A small chance each tick to freeze a cell for 1.2 s; bosses never freeze From the Codex Cold slows chemistry down: frozen viruses can stay infectious for years, which is how labs store them.
Frost Aura in the Codex Most hits miss you, and cells in the mist are poisoned.
About 56% of hits drift through you (up to 80% with Elemental Potency), shown as MISS Cells in the mist gain poison stacks every half second From the Codex Aerosols, the fine mist of a breath or cough, can hang in the air for hours carrying viruses.
Mist Veil in the Codex Heal over time while bursts of light burn nearby cells.
Heals 2.5% of max HP per second A burst of light every 1.3 s for 1× your damage From the Codex Ultraviolet light shreds viral genomes, which is why hospitals use UV lamps to disinfect rooms.
Radiance in the Codex A wide dark aura drains cells fast to heal you, drained cells burst into shadow novas, and your shots hit much harder.
Drains 0.9× your damage from every cell in the aura every 0.25 s, healing a quarter of it Cells drained dry burst for 1.5× your damage around them Your shots deal +60% damage From the Codex Out of sunlight, viruses on surfaces survive much longer; darkness protects them from UV.
Umbra in the Codex