Wiki Gear & Store Boss Sets Every organ boss always drops one named piece of its own five-piece set (in Pandemic Game Mode, an ordinary piece of the same tier instead). Set bonuses unlock at 3, 4 and 5 pieces worn and stack, so a full set has all three. A boss piece is the organ's best tier 40% of the time, one tier below 45% of the time and two below 15% of the time. Set pieces wear an outline and dot in their set's colour, and the Loadout shows how many of each set you wear.
On this page 8 Hemagglutinin Array Lipid Bilayer Replicase Complex Glycan Shield Capsomere Lattice Polymerase Engine Integrase Core Neurotropic Crown The Mast Cell's set, built for raw firepower.
Pieces: Histamine Crown, Histamine Mantle, Histamine Lattice, Histamine Talons, Histamine Lance(3) +15% damage (4) +1 projectile on every shot (40% damage) (5) Shots pierce 2 more cells, +20% damage Drops at Common (the Nasal Passage's top tier) From the Codex A tissue cell packed with granules of histamine and other chemicals that it releases to start inflammation.
Fun fact: Mast cells are best known for allergic reactions, but they also guard the nose, lungs and skin against infection.
Mast Cell in the Codex The Alveolar Macrophage's set, built for toughness.
Pieces: Surfactant Crown, Surfactant Mantle, Surfactant Lattice, Surfactant Talons, Surfactant Lance(3) +20% max HP (4) Block the first hit in every room (5) −10% damage taken, regenerate 1.5 HP/s Drops at Uncommon or Common From the Codex The lungs' resident macrophage. It patrols the air sacs and swallows dust, microbes and debris that get past the airways.
Fun fact: In smokers they fill up with soot, so pathologists sometimes call them "dust cells".
Alveolar Macrophage in the Codex The Plasma Cell's set, built around your ultimate.
Pieces: Plasma Crown, Plasma Mantle, Plasma Lattice, Plasma Talons, Plasma Lance(3) Ultimate charges 25% faster (4) Start each run with your ultimate charged (5) Ultimate radius +40%, Shift/Latency charges 50% faster Drops at Rare, Uncommon or Common From the Codex A fully matured B cell that has become an antibody factory, packed with endoplasmic reticulum.
Fun fact: A single plasma cell can release around 2,000 antibodies every second.
Plasma Cell in the Codex The Follicular Helper T Cell's set, built for stealth and ambushes.
Pieces: Germinal Crown, Germinal Mantle, Germinal Lattice, Germinal Talons, Germinal Lance(3) Detection rises 30% slower (4) Immune cells see 30% less far (5) Ambush hits deal +100% damage Drops at Rare, Uncommon or Common From the Codex A helper T cell that directs B cells in germinal centres, deciding which ones become antibody factories.
Fun fact: Germinal centres are where antibodies evolve to bind ever more tightly.
Follicular Helper T Cell in the Codex The Paneth Cell's set, built to tank and punish contact.
Pieces: Mucosal Crown, Mucosal Mantle, Mucosal Lattice, Mucosal Talons, Mucosal Lance(3) Take 10% less damage (4) Cells that touch you take 25 damage (5) Regenerate 2 HP/s, take 10% less damage Drops at Epic, Rare or Uncommon From the Codex A gut cell at the base of intestinal crypts that releases antimicrobial proteins called defensins.
Fun fact: Paneth cells also guard the gut's stem cells right next to them.
Paneth Cell in the Codex The Kupffer Cell's set, built for rate of fire.
Pieces: Kupffer Crown, Kupffer Mantle, Kupffer Lattice, Kupffer Talons, Kupffer Lance(3) Fire 15% faster (4) Shots fly 25% faster (5) +1 projectile on every shot (40% damage), fire 15% faster Drops at Legendary, Epic or Rare From the Codex The liver's resident macrophage, lining its blood vessels and filtering out bacteria, viruses and old red cells.
Fun fact: Kupffer cells make up most of the body's tissue macrophages.
Kupffer Cell in the Codex The Hematopoietic Stem Cell's set, built for sustain.
Pieces: Marrow Crown, Marrow Mantle, Marrow Lattice, Marrow Talons, Marrow Lance(3) +1% lifesteal on auto-attacks (4) Each kill heals 2 HP (5) +25% max HP, +15% damage Drops at Mythic, Legendary or Epic From the Codex The stem cell that gives rise to every blood and immune cell.
Fun fact: A single transplanted stem cell can rebuild a mouse's whole blood system.
Hematopoietic Stem Cell in the Codex The Microglia's set, built for critical hits and burst damage.
Pieces: Microglial Crown, Microglial Mantle, Microglial Lattice, Microglial Talons, Microglial Lance(3) +10% critical hit chance (4) +10% crit chance, ambush hits +50% (5) +30% damage Drops at Prismatic, Mythic or Legendary From the Codex The brain's resident immune cells, constantly sweeping with branching arms and swallowing debris or invaders.
Fun fact: Microglia also prune unused synapses as the brain develops.
Microglia in the Codex 
