Endless Game Mode

Endless Game Mode

Level 7

Fight wave after wave in the deepest organ you've reached and see how long you last.

• Opens at Level 7 for the selected virus
• Main menu button tagged “Collect: Ribozymes”
• Runs stand apart from your lineage: no inherited strain or inherited bonuses, and dying doesn't end a generation
• No XP, no host and no tumors
• “Endless Game Mode runs don't count toward your lineage or the Codex.”

The arena

Newest organ

The arena is the deepest organ you've reached in Infect Game Mode, and it's as hard as that organ.

• The start screen shows the arena, your best set there and the top gear tier it can drop
• “Reach the … in a normal run for a harder arena”
• Your best set is kept separately for each organ's arena
• One big sealed room with no minimap

Difficulty level

Difficulty 1–8

The arena's organ is its difficulty level, from 1 (Nasal Passage) to 8 (Brain).

• A DIFFICULTY badge sits on the arena card and in the pause menu
• Tap it for the organ ladder, how much health and damage cells have compared with Difficulty 1, and the best gear that can drop
• Each set adds +15% cell health, +8% damage and +3% speed (up to +60%), and elites turn up 15% more often; in a run the panel shows the current set's health multiplier
• The Endless card also says every boss is at least as tough as your deepest organ's boss
• The same panel shows how Pandemic Game Mode climbs, so both modes can be compared

Draft your strain

6 of 20

Every Endless run opens with a draft: pick 6 traits from a pool of 20.

• The same trait can show up twice; picking both stacks it
• Deeper arenas roll rarer traits
• “Pick for me” fills your picks; once full it becomes “Re-roll”
• Synergy hints on the cards

How a set plays

Set flow

Each set starts with a card of its rules, then a short countdown, its waves, and a moment to collect loot before the next pick.

• The set card lists its boons and curses; press Ready
• “SET n · STARTS IN 5”: you can move, nothing spawns yet
• Waves come one after another, 1.4 s apart once a wave is cleared
• Every hostile cell must be gone and stay gone for 3.5 s
• Then loot drops in the middle and you choose 1 of 3 traits

Set schedule

2 → 5 waves

Sets start at 2 waves and build up to 5, with a boss set every few sets.

• Sets 1–16: 2, 2, 2, BOSS, 3, 3, 2, BOSS, 3, 4, 4, BOSS, 5, 5, 5, BOSS
• After that every set has 5 waves, with a boss set after 3 sets, then 4, then 3, then 4…
• Boss sets in order: 4, 8, 12, 16, 20, 25, 29, 34…

The waves

Waves

Every cell arrives already hunting you, from the organ's own mix, and the mix grows as the sets and waves climb.

• Cells spawn at least 280 pt away from you
• They never give up the chase: every cell in the arena keeps coming for you (only Latency hides you for a while)
• Each wave adds an antibody swarm of 3 + the set number
• “WAVE n / N” announces each new wave; “FINAL WAVE · SET n” the last
• The top pill shows the set, wave and cells left

Rising difficulty

Every set

Every set is harder than the last, on top of its own rules.

• Cells +15% health per set after the first
• Cells hit +8% harder per set
• Cells +3% faster per set (up to +60%)
• Elites +15% more likely per set
• The set card says it: “Cells 30% tougher, hitting 16% harder than set 1”

Global effects

Boons & curses

Each set rolls new global boons and curses that last until the next set.

• 1 boon per set, 2 from set 5
• 1 curse in sets 1–2, then one more every 2 sets, up to 5 from set 9
• 11 boons and 11 curses in the pool

Boss sets

Boss

A boss set is one boss from any organ you've reached, never the same one twice in a row.

• Whichever organ's boss it is, it stands in for your deepest organ's boss: it gets that boss's health and contact damage (never less than its own)
• Its health never drops below what your deepest organ's boss gets in Infect Game Mode: 28 s of your damage in the Nasal Passage, 4 s more per organ deeper (56 s in the Brain), plus 3 s for each earlier boss set; its elite tier and affixes come on top
• It fades in across the arena from you
• A boss from an organ you've passed waits 30% less between attacks and stays open 30% shorter (one organ back), 10% more per organ further back, up to 50%
• When it shields, its reinforcements are as tough as the arena's own cells, and in the Liver arena every boss's attacks and signature skill come 35% sooner, as the Liver's own boss does
• “BOSS SET · <boss> · Beat it for extra loot”
• A boss from an earlier organ says it was scaled up: “Scaled up to Difficulty 8. Beat it for extra loot” when your deepest organ is the Brain

Set rewards

Loot

Every cleared set pays nucleotides, materials and gear of the arena's level, and heals you.

• Nucleotides: 30 + 18 per set (scaled by organ and modifiers)
• Polymerase Shards: 4 + the set number
• Chaperone Proteins on every even set
• Ribozyme Cores every set: 1, 2 from set 6, 3 from set 12…
• A gear piece every set (better from set 6), a second every 3rd set
• Boss sets add a better gear piece and more Ribozyme Cores
• Heals 30% of your max health

Ribozyme Cores

Endless drop

The material that enhances gear from +3 up to +10; every level needs more of them.

• Every Endless set pays at least one, more as sets climb
• Endless bosses, Killer T cells and elites drop more
• In Infect and Pandemic Game Modes those drops condense into chaperones

Cover walls

7 layouts

Every set raises a new layout of tissue walls to hide behind, bounce shots off and funnel cells.

• Four pillars, two long bars, corner brackets, vertical baffles, scattered blocks, staggered bars, or a diamond of short walls
• Layouts can be mirrored and never repeat back to back
• Walls never rise on top of you or the loot in the middle
• Each piece is a raised mound of the organ's tissue, like the islands and inner walls in its rooms

Endless over

Run end

The run summary counts sets survived, then a final page shows your result against your best.

• “Sets survived: N · Best: N”
• Gear found can be reviewed, equipped or dismantled as usual
• “Endless Game Mode runs don't count toward your lineage.”