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Organ 6 of 8

Liver

The body's filter. Rust-red hexagonal lobules, each with a dark central vein, patrolled by near-invisible NKT cells and stellate cells that leave scar tissue behind.

Threat enemy damage ×7.5, enemy health ×19, rewards ×4Size 20–24 roomsIn The Eight Organs
The Halovirus faces the Polyploid Hepatocyte, the Liver's key guardian
The Halovirus faces the Polyploid Hepatocyte, the Liver's key guardian

Who you meet here

Organ facts

Objective
"Survive the Kupffer Cell's filter"
Boss
Kupffer Cell, "The liver's resident filter"
Key guardian
Polyploid Hepatocyte (Awakened), holding the Fusion Peptide
Cancer
Hepatocellular Carcinoma (it regenerates from its lobes, so kill every lobe before they regrow, then strike). Its assassin is the Hepatoid Regenerator
Hazards
bile ducts that spray jets across the room
Local cells
Neutrophils, Stellate Cells, NKT Cells, Macrophages, Monocytes and Complement. Deeper rooms add IgA Plasma Cells, antiviral capsules and vaccine vials
Look
a dark rust floor tiled with hexagonal lobules and central veins, inside walls of hepatocyte plates, rows of boxy cells with round nuclei
Music
B minor at 104 BPM, a triangle pad under a sawtooth lead
Size
20–24 rooms
Threat
enemy damage ×7.5, enemy health ×19, rewards ×4

Also in the Liver

Tissue Hazards & TerrainOrgans & Bosses

Tumor PartsCancer

Tumor AttacksCancer

Organ MilestonesViruses

The Organ MapIn a Run

Boss SetsGear & Store

Audio & PresentationGame Modes

Found in every organ

From the Codex

The body's chemical factory and filter. Blood from the gut flows through its hexagonal lobules, where resident macrophages catch anything foreign.

Fun fact: The liver can regrow from as little as a quarter of its original size.

Liver in the Codex