Codex
Conditions that change how a host plays.
In type 1 diabetes the immune system destroys insulin-making cells; high blood sugar slows wound healing and weakens immune cells.
In the game
Sugary blood: +60% nucleotides and immune cells 15% slower. But rooms heal you 70% less.
A condition people can have.
Appears inHost Conditions
Some people are born with a weakened immune system (like SCID, 'bubble boy disease') and catch infections far more easily.
In the game
Weak immune system: cells have 45% less HP, fewer of them, far fewer elites. But you earn 40% fewer nucleotides.
A condition people can have.
Appears inHost Conditions
Lupus is an autoimmune disease: the immune system attacks the body's own tissues, causing widespread inflammation.
In the game
The immune system attacks itself: dying cells burst and hurt their neighbours, +50% nucleotides. But every cell starts alert and hits 30% harder.
A condition people can have.
Appears inHost Conditions
A fever above about 41°C is a medical emergency. Fever speeds up immune cells, but extreme heat damages the body too.
In the game
Everything runs hot: you fire 25% faster and move 20% faster. But cells move 30% faster and their shots fly 25% faster.
A condition people can have.
Appears inHost Conditions
Sepsis is the body's extreme, life-threatening response to an infection, when the immune response spirals out of control.
In the game
The body is overwhelmed: double nucleotides, more mutation orbs. But 70% more cells per room and 2 extra rooms per area.
A condition people can have.
Appears inHost Conditions
Sickle cell disease bends red blood cells into crescents; carrying one copy of the gene protects against malaria.
In the game
Sickled red cells: you move 20% faster and land 15% critical hits. But you have 30% less max HP.
A condition people can have.
Appears inHost Conditions
Cystic fibrosis makes mucus thick and sticky, clogging the lungs and gut and trapping microbes.
In the game
Thick mucus everywhere: cells move 30% slower and see 30% less far. But you move 15% slower too.
A condition people can have.
Appears inHost Conditions
Long-term stress and lack of sleep raise cortisol, which disrupts the immune system's normal rhythm.
In the game
A stressed host: +50% nucleotides and 10% critical hits. But Detection starts at 30, rises 70% faster and barely cools.
A condition people can have.
Appears inHost Conditions
In hemophilia a clotting factor is missing, so bleeding takes much longer to stop. It ran through Europe's royal families.
In the game
Blood won't clot: +40% damage. But clearing rooms never heals you.
A condition people can have.
Appears inHost Conditions
Anaphylaxis is a severe allergic reaction where mast cells release histamine all at once.
In the game
Allergic overreaction: +80% nucleotides, double RNA, many more elites. But cells have 30% more HP and hit 20% harder.
A condition people can have.
Appears inHost Conditions
In asthma the airways swell and narrow; respiratory viruses are a common trigger of attacks.
In the game
Narrowed airways: cells move 20% slower, +30% nucleotides. But you move 10% slower and there are more pits.
A condition people can have.
Appears inHost ConditionsThe Codex
Post-viral fatigue can leave people exhausted for months after an infection, with an immune system that hasn't fully settled.
In the game
An exhausted immune system: cells have 20% less HP and hit 15% softer. But far fewer mutation orbs and RNA.
A condition people can have.
Appears inHost Conditions
Metastasis is when cancer spreads from where it started to other organs through the blood or lymph.
In the game
The host is riddled with cancer: every organ grows a tumor that starts a stage bigger, grows faster and spreads twice more. Tumors pay out triple and the run pays +30%.
A condition people can have.
Appears inOncolytic VirusHost Conditions
Chemotherapy kills fast-dividing cells: cancer, but also immune cells, which is why patients catch infections easily.
In the game
The drugs wipe out immune cells (30% less HP, hit 20% softer) and shrink tumors (they take 50% more damage). But they poison you too: −20% max HP.
A condition people can have.
Appears inOncolytic VirusHost Conditions
White-nose syndrome is a fungal disease that has killed millions of North American bats since 2006.
In the game
A fungus covers the bat: cells see half as far and +60% nucleotides. But you can only see a small circle around you.
Found in: Fruit Bat.
Appears inHost Conditions
Rabies infects the brain and makes animals aggressive; it's nearly 100% fatal once symptoms start.
In the game
A rabid host: +30% damage. But every cell is already alert and moves 40% faster.
Found in: Fruit Bat, Dog, White-Tailed Deer, Reindeer.
Appears inHost Conditions
African swine fever kills nearly all infected pigs and has spread across Asia and Europe since 2018.
In the game
The pig's cells are dying: they have 35% less HP. But 60% more of them per room.
Found in: Pig.
Appears inHost Conditions
Mad cow disease (BSE) is caused by misfolded prion proteins that leave the brain full of tiny holes.
In the game
Spongy, prion-riddled tissue: cells see 60% less far and Detection rises 60% slower. But the floor is full of holes (far more pits).
Found in: Dairy Cow.
Appears inHost Conditions
H5N1 bird flu has spread worldwide in wild birds since 2021; when two flu strains meet, they can swap genes.
In the game
Another flu strain to swap genes with: +40% damage, +30% nucleotides. Competing for the same cells: cells have 20% more HP.
Found in: Chicken, Mallard Duck, Herring Gull, Pigeon, Penguin, Seal.
Appears inHost Conditions
Canine distemper is a measles-like virus that attacks dogs' breathing, gut and nervous system.
In the game
Weakened by distemper: cells have 25% less HP. But dying cells burst and can hurt you.
Found in: Dog, Seal.
Appears inHost Conditions
Chronic wasting disease is a prion disease of deer and elk that slowly wastes them away.
In the game
A wasting deer: cells have 40% less HP. But you have 30% less max HP and cells hit 20% harder.
Found in: White-Tailed Deer, Reindeer.
Appears inHost Conditions
Some SIV strains cause AIDS-like disease in monkeys and apes, just as HIV does in people.
In the game
SIV already wrecked its defences: cells have 45% less HP, few elites. But you earn 20% fewer nucleotides.
Found in: Chimpanzee, Macaque, Capuchin Monkey, Ring-Tailed Lemur.
Appears inHost Conditions
Botulism toxin, made by bacteria in stagnant water, paralyses waterbirds and kills thousands each year.
In the game
Paralysing toxin: cells move 45% slower. But you move 20% slower and fire 15% slower.
Found in: Mallard Duck, Herring Gull, Penguin.
Appears inHost Conditions
Pigeon paramyxovirus makes birds twitch, twist their necks and lose balance.
In the game
A dizzy, twitching host: you move 25% faster and dash 40% more often. But enemy shots fly 30% faster.
Found in: Pigeon.
Appears inHost Conditions
Marek's disease is a herpesvirus of chickens that causes tumors; its vaccine was the first against a cancer.
In the game
Tumorous tissue everywhere: cells have 20% less HP, +40% nucleotides. But 3 extra rooms per area.
Found in: Chicken.
Appears inHost Conditions
Fruit bats carry Nipah virus without getting sick; it has spilled over to pigs and people in Asia.
In the game
Another virus lives here: you deal 15% less damage. But triple RNA and +50% nucleotides.
Found in: Fruit Bat, Pig.
Appears inHost Conditions
Hibernating bats drop their body temperature and immune activity, which lets fungi and viruses take hold.
In the game
A hibernating bat: cells move half as fast and Detection rises half as fast. But the cold slows your fire rate 30%.
Found in: Fruit Bat.
Appears inHost Conditions
Pigs catch both bird and human flu; the 2009 pandemic strain was assembled inside pigs.
In the game
Pig flu to swap genes with: +35% damage, double mutation orbs.
Found in: Pig.
Appears inHost Conditions
Foot-and-mouth disease causes painful blisters in cattle and pigs; the 2001 UK outbreak led to millions of animals being culled.
In the game
Blistered tissue: cells that touch you take 15 damage, +30% nucleotides. But you move 15% slower.
Found in: Dairy Cow, Pig, Dromedary Camel, Kangaroo, Llama.
Appears inHost Conditions
Bovine tuberculosis forms granulomas, balls of immune cells walling off the bacteria.
In the game
Granulomas wall off infection: fewer cells, +60% nucleotides. But they have 40% more HP and elites are common.
Found in: Dairy Cow, Dromedary Camel, Llama.
Appears inHost Conditions
Newcastle disease is a paramyxovirus of poultry that attacks the nervous system.
In the game
Nervous-system damage: cells move 30% slower. But every cell is already alert.
Found in: Chicken, Pigeon.
Appears inHost Conditions
Fowlpox is a poxvirus spread by mosquitoes that causes wart-like lesions on birds.
In the game
Pox lesions: cells have 30% less HP. But wounded cells slowly regenerate.
Found in: Chicken.
Appears inHost Conditions
Duck plague (duck viral enteritis) is a herpesvirus that causes internal bleeding in ducks and geese.
In the game
A haemorrhaging host: dying cells burst and hurt neighbours, +50% nucleotides. But the bursts can hurt you too.
Found in: Mallard Duck.
Appears inHost Conditions
West Nile virus cycles between birds and mosquitoes and can infect the brain of birds, horses and people.
In the game
A mosquito-borne brain infection: double RNA, cells see 40% less far. But they hit 25% harder.
Found in: Mallard Duck, Herring Gull, Pigeon.
Appears inHost Conditions
Oil from spills mats seabird feathers, destroying their waterproofing and insulation.
In the game
Slick feathers: you move 10% faster, dash 40% more often and enemy shots are 20% slower. But rooms heal you half as much.
Found in: Herring Gull, Penguin.
Appears inHost Conditions
Canine parvovirus attacks rapidly dividing cells in the gut and is often deadly to unvaccinated puppies.
In the game
Parvovirus wrecked the gut: cells have 40% less HP. But you have 25% less max HP.
Found in: Dog.
Appears inHost Conditions
Canine influenza viruses jumped to dogs from horses (H3N8) and birds (H3N2).
In the game
Dog flu to mix with: you fire 25% faster, +20% nucleotides.
Found in: Dog.
Appears inHost Conditions
Epizootic hemorrhagic disease, spread by biting midges, causes fever and bleeding in deer.
In the game
Haemorrhagic fever: dying cells burst and hurt neighbours, +40% nucleotides. But cells hit 25% harder.
Found in: White-Tailed Deer, Reindeer.
Appears inHost Conditions
Studies found human viruses spreading widely among wild white-tailed deer.
In the game
Another virus already here: −10% damage. But cells have 30% less HP and Detection rises 30% slower.
Found in: White-Tailed Deer.
Appears inHost Conditions
Ebola outbreaks have killed large numbers of wild chimpanzees and gorillas.
In the game
The host is collapsing: 40% fewer cells with 30% less HP. But you have 25% less max HP and Detection starts at 40.
Found in: Chimpanzee.
Appears inHost Conditions
Mpox is a poxvirus that circulates in animals including primates and rodents and can spread to people.
In the game
Pox lesions: cells that touch you take 20 damage, 10% critical hits. But 30% more cells per room.
Found in: Chimpanzee, Macaque, Capuchin Monkey, Ring-Tailed Lemur.
Appears inHost Conditions
Parasitic worms compete with their host for nutrients and can dampen immune responses.
In the game
Worms steal the host's food: cells have 30% less HP. But you earn 30% fewer nucleotides.
Found in: Fruit Bat, Dairy Cow, Pig, Chicken, Dog, Mallard Duck, White-Tailed Deer, Herring Gull, Chimpanzee, Pigeon, Penguin, Seal, Dromedary Camel, Kangaroo, Macaque, Capuchin Monkey, Llama, Ring-Tailed Lemur, Reindeer.
Appears inHost ConditionsAnimal Hosts
A poorly fed body makes fewer immune cells and fights infections less well.
In the game
A starving host: 30% fewer cells, 10% slower. But you have 20% less max HP.
Found in: Fruit Bat, Dairy Cow, Pig, Chicken, Dog, Mallard Duck, White-Tailed Deer, Herring Gull, Chimpanzee, Pigeon, Penguin, Seal, Dromedary Camel, Kangaroo, Macaque, Capuchin Monkey, Llama, Ring-Tailed Lemur, Reindeer.
Appears inHost Conditions
Bacterial pneumonia often follows a viral infection once the airways' defences are damaged.
In the game
Lungs full of bacteria: cells are distracted (see 40% less far), +30% nucleotides. But 40% more cells per room.
Found in: Fruit Bat, Dairy Cow, Pig, Chicken, Dog, Mallard Duck, White-Tailed Deer, Herring Gull, Chimpanzee, Pigeon, Penguin, Seal, Dromedary Camel, Kangaroo, Macaque, Capuchin Monkey, Llama, Ring-Tailed Lemur, Reindeer.
Appears inHost Conditions
Ticks spread Lyme disease bacteria, which cause long-lasting inflammation.
In the game
Tick-borne inflammation: 10% critical hits, +40% nucleotides. But wounded cells regenerate.
Found in: Fruit Bat, Dairy Cow, Pig, Chicken, Dog, Mallard Duck, White-Tailed Deer, Herring Gull, Chimpanzee, Pigeon, Penguin, Seal, Dromedary Camel, Kangaroo, Macaque, Capuchin Monkey, Llama, Ring-Tailed Lemur, Reindeer.
Appears inHost Conditions
Overheating forces the body to divert resources, weakening immune defences.
In the game
An overheated host: you move 15% faster and dash 30% more often. But 15% less max HP and faster enemy shots.
Found in: Fruit Bat, Dairy Cow, Pig, Chicken, Dog, Mallard Duck, White-Tailed Deer, Herring Gull, Chimpanzee, Pigeon, Penguin, Seal, Dromedary Camel, Kangaroo, Macaque, Capuchin Monkey, Llama, Ring-Tailed Lemur, Reindeer.
Appears inHost Conditions
Lead from old bullets and fishing weights poisons wildlife and suppresses the immune system.
In the game
Poisoned tissue: cells hit 25% softer and Detection rises 30% slower. But they have 25% more HP.
Found in: Fruit Bat, Dairy Cow, Pig, Chicken, Dog, Mallard Duck, White-Tailed Deer, Herring Gull, Chimpanzee, Pigeon, Penguin, Seal, Dromedary Camel, Kangaroo, Macaque, Capuchin Monkey, Llama, Ring-Tailed Lemur, Reindeer.
Appears inHost Conditions
Hosts are often infected with more than one virus at once; viruses sharing a cell can swap genes.
In the game
Another virus is already here: you start with a random trait of the host's genome tier. But the immune system is primed: cells have 15% more HP.
A condition people can have.
Appears inHost Conditions
