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Organs & Bosses
A full run goes nose to brain through eight organs. Each has its own look, music, local cells and tissue hazards, a key guardian holding a gene, a cancer, and a boss you must beat to break through.
The eight organs, nose to brain
Articles
The JourneyThe Eight OrgansEvery Infect Game Mode run is a descent through the host, one organ at a time. Each organ has its own map, local…8
Boss FightsOrgan BossesAt the end of every organ, a giant immune cell guards the way on. Bosses pick their attacks at random, never repeat…9
Keys & LocksKey Guardians & GenesEvery organ seals one door with living tissue. The gene that opens it waits in a gene chamber guarded by a key…14
Living TissueTissue Hazards & TerrainThe host's own tissue fights back, but it doesn't take sides. Every organ has its own hazards, and they hurt immune…16
The EndThe EndingDefeat the Microglia in Infect Game Mode and the host is yours.1Key numbers
| Organs to infect | 8 |
|---|---|
| Organ bosses | 8 |
| Key guardians (mini-bosses) | 8 |
| Genes that open sealed doors | 3 |
| Kinds of sealed door | 3 (mucus plug, tight junction, fibrin clot) |
| Organ cancers | 8 |
| Tissue hazard types | 11 |
| Boss shield phases | 2 (at 2/3 and 1/3 health) |
| Boss signature skills | 6 |
| Guardian stages | 3 (normal, Awakened, Ancient) |
| Blood-brain barrier | 38% less damage taken by every Brain cell |
| Rooms per organ | 12–16 (Nasal Passage) up to 22–26 (Brain) |