
Volatile Payload
UniqueDying cells burst and hurt their neighbours.
- Bosses don't burst
From the Codex
Lytic viruses burst their host cells, releasing virions and inflammatory debris all at once.
Lysis Cascade in the Codex
Signature effects
Eight signature effects. They roll on Legendary (1), Mythic (2) and Prismatic (3) gear, and a Bonus ability mutation can add one to a piece of any tier. Uniques show in orange on the piece.

Dying cells burst and hurt their neighbours.
Lytic viruses burst their host cells, releasing virions and inflammatory debris all at once.
Lysis Cascade in the Codex
Cells that touch you take 20 damage.
Some viral proteins damage the membranes of immune cells that try to grab them.
Barbed Spikes in the Codex
+1 projectile on every shot (40% damage).
Gene duplication gives a virus a spare copy of a gene that can take on a new job.
Twin Genome in the Codex
Block the first hit in every room.
Dense glycan coats on envelope proteins physically shield viruses from antibodies.
Envelope Shield in the Codex
Start each run with Shift (Latency for Retrovirus) and your ultimate charged.
Strong promoters can switch a virus's genes on faster and louder than usual.
Overcharged in the Codex
Auto-attacks heal 1% of their damage.
Viruses reprogram cell metabolism to siphon off nutrients and building blocks for themselves.
Vampiric Uptake in the Codex
Immune cells see 40% less far.
Antigenic variation changes the parts of a virus antibodies recognize, letting it slip past immunity.
Evasive Proteins in the Codex
Fire 20% faster.
Faster polymerases and assembly let some strains release new virions hours earlier.
Rapid Assembly in the Codex